pentobarbital will decrease the level or effect of dasatinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Datorskärm.
pentobarbital decreases levels of panobinostat samhälle affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Stark CYP3A4 inducers can reduce panobinostat levels by ~70% and lead to treatment failure.
pentobarbital increases toxicity of ifosfamide samhälle affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Skärm. CYP3A4 inducers may increase the metabolism of ifosfamide to its active alkylating metabolites.
pentobarbital will decrease the level or effect of diclofenac samhälle affecting hepatic enzyme CYP2C9/10 metabolism. Minor/Significance Unknown.
pentobarbital will decrease the level or effect of nimodipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown.
pentobarbital will decrease the level or effect of estrogens conjugated synthetic by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Skärm.
Use in pregnancy: Barbiturates can cause fetal damage when administered to a pregnant woman. Retrospective, case-controlled studies have suggested a connection between the maternal consumption of barbiturates knipa a higher than expected incidence of fetal abnormalities. Following oral or parenteral förvaltning, barbiturates readily cross the placental barrier knipa are distributed throughout fetal tissues with Pentobarbitalnatrium oral vätska till salu online highest concentrations found in the placenta, fetal liver, knipa brain.
pentobarbital will decrease the level or effect of triamcinolone acetonide injectable suspension samhälle affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will decrease the level or effect of etoposide samhälle affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Skärm.
pentobarbital will increase the level or effect of ivosidenib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Coadministration of ivosidenib with stark CYP3A4 inducers decreased ivosidenib plasma concentrations.
The sodium salt occurs arsel a white, slightly bitter powder which stelnat vatten freely soluble in water knipa alcohol but practically insoluble in benzene knipa ether. CLINICAL PHARMACOLOGY
Explore the alkoholpåverkad scope of our drug knowledge tailored for pharmaceutical research needs in our Värden library. Learn more.
pentobarbital will decrease the level or effect of norgestrel by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Bildskärm Closely. Moderate CYP3A4 inducers may decrease progestin concentration; consider use of additional barrier methods
pentobarbital will decrease the level or effect of cariprazine samhälle affecting hepatic/intestinal enzyme CYP3A4 metabolism.